The blood-brain barrier redefined
✍ Scribed by K. Felgenhauer
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 112 KB
- Volume
- 233
- Category
- Article
- ISSN
- 0340-5354
No coin nor oath required. For personal study only.
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Efflux transport at the blood-brain barrier (BBB) limits the brain tissue exposure to a variety of potential therapeutic agents, including compounds that are relatively lipophilic and would be predicted to permeate the endothelial lining of the brain microvasculature. Recent advances in molecular an
## Abstract Few terms in the biomedical lexicon are as widely recognized as the phrase blood–brain barrier (BBB). Indeed, it immediately conjures up a “barricade” between the blood and the brain, a feature often considered more obstacle than safeguard. In truth, the BBB performs in both capacities,