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The Bisphosphonate Zoledronic Acid Induces Cytotoxicity in Human Myeloma Cell Lines with Enhancing Effects of Dexamethasone and Thalidomide

โœ Scribed by A. Ugur Ural; M. Ilker Yilmaz; Ferit Avcu; Aysel Pekel; Murat Zerman; Oral Nevruz; Ali Sengul; Atilla Yalcin


Publisher
Carden Jennings Publishing
Year
2003
Tongue
English
Weight
318 KB
Volume
78
Category
Article
ISSN
0925-5710

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## Interleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1 Like many other cytokines and growth factors, interleukin-6 (IL-6) activates ~21'"'. However, the precise biochemical mechanisms ind