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The birth and life of lipid droplets: learning from the hepatitis C virus

✍ Scribed by Philippe Roingeard; Marion Depla

Book ID
114424327
Publisher
Portland Press
Year
2011
Tongue
English
Weight
551 KB
Volume
103
Category
Article
ISSN
0248-4900

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Hepatitis C virus (HCV) relies on host lipid metabolic pathways for its replication, assembly, secretion, and entry. HCV induces de novo lipogenesis, inhibits Ξ²-oxidation, and lipoprotein export resulting in a lipid-enriched cellular environment critical for its proliferation. We investigated the ef