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The birch reduction of heterocyclic compounds V Birch reduction of 2- and 5-acylfuran-3-carboxylic acids and reductive elimination of 2-(arylmethoxymethyl)furan-3-carboxylic acids
✍ Scribed by Yasuo Ohta; Matsumi Doe; Yoshiki Morimoto; Takamasa Kinoshita
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2000
- Tongue
- English
- Weight
- 283 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
The Birch reduction of 2‐ and 5‐acylfuran‐3‐carboxylic acid 1 and 4 gave 2‐acyl‐2,3‐dihydrofuran‐3‐carboxylic acid 2 and 5‐acyltetrahydrofuran‐3‐carboxylic acid 5, respectively. Further examination of the reductive elimination was also studied on 2‐(arylmethoxymethyl)furan‐3‐carboxylic acids 7.
📜 SIMILAR VOLUMES
## Abstract The Birch reduction of 2‐(1‐alkoxyalkyl)furan‐3‐carboxylic acids 1a‐f gave 2‐alkyl‐3‐furancarboxylic acids 2a‐f with loss of the alkoxyl group in excellent isolated yields.
## Abstract The Birch reduction of 3‐acylfurans 1, 3 and 10 and their reaction path ways are described.