The biosynthesis of stable cobaltoproteins by plants. II. Interaction of iron and cobalt metabolism in neurospora crassa
✍ Scribed by Ballentine, Robert
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1953
- Tongue
- English
- Weight
- 495 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0095-9898
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✦ Synopsis
I n a former publication (Ballentine and Stephens, '51) it was demoiistrated that in plants and microorganisms, especially Neurospora crassa, the metabolism of cobalt involves its incorporation into stable protein complexes. By exchange and complexing reactions it was shown that these complexes were non-ionic in nature, and that they were formed only during the growth and metabolism of the organism. Their protein nature was construed from their precipitability by trichloroacetic acid and their failure to dialize. At that time the question was raised that, while the level of this metabolism is of the order of magnitude of vitamin B,, metabolism in other organisms (Euglenza gracilis), there exists the possibility that the cobalt is being metabolically incorporated into the cytoplasm in place of iron by a metabolic mistake. The experiments reported in this paper were set up to test this point, and by means of covariance analysis of the data, such a metabolic mistake seems very improbable. It appears that the metabolism of cobalt pertains directly to this element and not to iron.