𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The biosynthesis of mycolic acids by Mycobacteria: current and alternative hypotheses

✍ Scribed by Cécile Asselineau; Jean Asselineau; Gilbert Lanéelle; Marie-Antoinette Lanéelle

Book ID
117330442
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
326 KB
Volume
41
Category
Article
ISSN
0163-7827

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of methyl (Z)-tetracos-5-enoat
Synthesis of methyl (Z)-tetracos-5-enoate and both enantiomers of ethyl (E)-6-methyltetracos-4-enoate: possible intermediates in the biosynthesis of mycolic acids in mycobacteria
✍ Gurdyal S. Besra; David E. Minnikin; Paul R. Wheeler; Colin Ratledge 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 827 KB

The high molecular weight 2-alkyl-3-hydroxy mycolic acids are key structural components of the cell envelope of pathogenic mycobacteria, such as Mycobacterium tuberculosis. A prime target for drug action would be the initial stages where the biosynthetic pathways diverge from those of ordinary fatty

The Specificity of Methyl Transferases I
The Specificity of Methyl Transferases Involved in trans Mycolic Acid Biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis
✍ Benjamin G. Schroeder; Clifton E. Barry 3rd 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 299 KB

Trans mycolic acid content is directly related to cell wall fluidity and permeability in mycobacteria. Carbon-13 NMR spectroscopy of mycolic acids isolated from Mycobacterium tuberculosis (MTB) and Mycobacterium smegmatis (MSM) fed 13 C-labeled precursor molecules was used to probe the biosynthetic