Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. CD133, a transmembrane glycoprotein, is an important cell surface marker for both stem cells and cancer stem cells in various tissues including liver. CD133 expression has been recently linked to poor prognosis
The biology of stem cell factor, a new hematopietic growth factor involved in stem cell regulation
โ Scribed by Maria Cristina Galli; Patricia-Jane V. Giardina; Anna Rita Migliaccio; Giovanni Migliaccio
- Book ID
- 110573239
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 784 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0940-5437
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In vivo, stem cell factor (SCF) exists in both a bound and soluble isoform. It is believed that the bound form is more potent and fundamentally required for the maintenance of hematopoietic stem cells (HSCs). This theory is supported by the observation that steel-Dickie mice lacking the bound isofor
## Understanding the Factors That Influence the Fate of Stem Cells Ever since the first human embryonic stem cell line was established, hopes have been raised that treatment for a wide range of cellular degenerative disease and injuries is imminent. While significant progress has been made in stem