𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The biology of Epstein-Barr virus: lessons learned from the virus and the host

✍ Scribed by Jeffrey I. Cohen

Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
695 KB
Volume
11
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

✦ Synopsis

Recent studies indicate that a large proportion of cytotoxic T cells are directed towards the Epstein-Barr virus (EBV) during both acute infection and convalescence. The virus, in turn, has usurped cellular pathways to promote proliferation of infected cells and has pirated cellular genes into its genome to modulate the immune system to allow lifelong infection of humans. Analysis of the immune response to the virus is leading to novel therapies for EBV-associated malignancies, including the use of virus-specific cytotoxic T cell infusions.

πŸ“œ SIMILAR VOLUMES

Structural genomics of the Epstein–Barr
Structural genomics of the Epstein–Barr virus
✍ Tarbouriech, Nicolas ;Buisson, Marlyse ;GΓ©oui, Thibault ;Daenke, Susan ;Cusack, πŸ“‚ Article πŸ“… 2006 πŸ› International Union of Crystallography 🌐 English βš– 565 KB

Epstein–Barr virus is a herpesvirus that causes infectious mononucleosis, carcinomas and immunoproliferative disease. Its genome encodes 86 proteins, which provided targets for a structural genomics project. After updating the annotation of the genome, 23 open reading frames were chosen for expressi

Elevated antibody titers to Epstein-Barr
Elevated antibody titers to Epstein-Barr virus prior to the diagnosis of Epstein-Barr-virus-associated gastric adenocarcinoma
✍ Paul H. Levine; Grant Stemmermann; Evelyne T. Lennette; Allan Hildesheim; Darryl πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 352 KB πŸ‘ 1 views

Epstein-Barr virus (EBV) has recently been identified in the tumor cells of patients with gastric carcinoma. We tested pre-morbid serum samples from a carefully monitored cohort of Japanese men in order to investigate the possibility that patients with EBV-associated gastric cancer represent a sub-s