## Weekly Vinorelbine Is An Effective Palliative Regimen after Failure with Anthracyclines and Taxanes in Metastatic Breast Carcinoma W e would like to dispute some of the statements made in the article by Zelek et al. 1 in Volume 92, Issue 9. The authors state that "currently, there is no gold st
The biology of breast carcinoma
โ Scribed by Judith Clancy Keen; Nancy E. Davidson
- Book ID
- 102106444
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 108 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
The biology of breast carcinoma is complex, with multiple factors contributing to its development and progression. The current review focuses on the role of several critical genes including estrogen receptor, progesterone receptor, retinoic acid receptor-beta, epidermal growth factor receptor family members, p53, BRCA1, and BRCA2 as risk factors for the development of disease, predictors of prognosis and response to therapy, and as therapeutic targets. Studies of the biology of these and other genes that contribute to the development and progression of breast carcinoma have had and will continue to have great impact on all aspects of disease management.
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