The Biochemistry of Myelin in X-Linked Mutants
โ Scribed by RICHARD H. QUARLES
- Book ID
- 119865250
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 747 KB
- Volume
- 605
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
There are several X-linked diseases in animals and at least one in man in which there is a failure of CNS myelination. We have recently cloned cDNAs for lipophilin (PLP) with which PLP sequences were localized to a region of the long arm of the X chromosome (Xq13-q22 in man) close to the jimpy up) l
## Abstract The prospect to create mouse mutants of virtually any cloned gene has renewed interest in the genetic analysis of mammalian brain development. A diverse group of spontaneous and engineered mouse mutants, characterized by a defect of myelin formation, has been intensively studied from th