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The Biochemistry of 3-End Cleavage and Polyadenylation of Messenger RNA Precursors

✍ Scribed by Wahle, Elmar; Keller, Walter


Book ID
120944752
Publisher
Annual Reviews
Year
1992
Tongue
English
Weight
786 KB
Volume
61
Category
Article
ISSN
0066-4154

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The end of the message: 3'– end processi
✍ Elmar Wahle πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 792 KB

## Abstract Almost all messenger RNAs carry a polyadenylate tail that is added in a post‐transcriptional reaction. In the nuclei of animal cells, the 3'‐end of the RNA is formed by endonucleolytic cleavage of the primary transcript at the site of poly (A) addition, followed by the polymerisation of