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The biochemical studies on phalloidin-induced cholestasis in rats

✍ Scribed by Kaoru Ishizaki; Shigemasa Kinbara; Norio Miyazawa; Yoshishige Takeuchi; Norio Hirabayashi; Hiroshi Kasai; Tsutomu Araki


Book ID
119538797
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
513 KB
Volume
90
Category
Article
ISSN
0378-4274

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Administration of phalloidin, one of the toxic peptides of the mushroom Amanita phalloides, leads to rapid and sustained cholestasis in rats. Although attributed to the interaction of phalloidin with microfilaments, the events leading to cholestasis are incompletely understood. The adenosine triphos