The binding of the calcium channel blocker, bepridil, to calmodulin
β Scribed by Itoh Hiroo; Tanaka Toshio; Mitani Yoshihide; Hidaka Hiroyoshi
- Book ID
- 115779133
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 384 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0006-2952
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The Ca2+ channel blockers felodipine and bepridil are known to affect selectively functions of calmodulin. We studied their effects on calmodulin binding and ATPase activities of calmodulin-containing and calmodulin-depleted rabbit heart sarcolemma. Both drugs as well as the specific anti-calmodulin
Specific binding of the calcium antagonist [3H]verapamil to a microsomal fraction, a presumptive plasma membrane fraction and an intracellular membrane fraction of the phototactic unicellular green alga Chlamydomonas reinhardtii has been demonstrated. The specific activity of the plasma membrane mar