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The Binding of Some Sulfonamides by Bovine Serum Albumin

โœ Scribed by Klotz, Irving M.; Walker, F. Marian


Book ID
118209502
Publisher
American Chemical Society
Year
1948
Tongue
English
Weight
459 KB
Volume
70
Category
Article
ISSN
0002-7863

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Structure relationship for binding of su
โœ Par-Lin Hsu; Joseph K. H. Ma; H. W. Jun; Louis A. Luzzi ๐Ÿ“‚ Article ๐Ÿ“… 1974 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 458 KB

The binding constants and the number of binding sites for the binding of 11 sulfonamide and seven penicillin derivatives to bovine serum albumin were determined using a fluorescence probe method. The results demonstrate that these drugs bind to hydrophobic sites on the serum albumin. The binding aff