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The binding cavity of mouse major urinary protein is optimised for a variety of ligand binding modes

✍ Scribed by Thelma A. Pertinhez; Elena Ferrari; Emanuela Casali; Jital A. Patel; Alberto Spisni; Lorna J. Smith


Book ID
116299405
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
504 KB
Volume
390
Category
Article
ISSN
0006-291X

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The mouse major urinary proteins (MUPs) are an ensemble of isoforms secreted by adult male mice and involved in sexual olfactory communication. MUPs belong to the lipocalin superfamily, whose conserved structure is a beta-barrel made of eight antiparallel beta-strands forming a hydrophobic pocket th