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The bicyclo[2.1.1]hexan-2-one system: a new probe for the experimental and computational study of electronic effects in π-facial selectivity in nucleophilic additions

✍ Scribed by Goverdhan Mehta; S.Robindro Singh; Vanessa Gagliardini; U.Deva Priyakumar; G.Narahari Sastry

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
79 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

The remotely substituted 5-exo-bicyclo[2.1.1]hexan-2-one system is introduced as a new probe to study long range electronic effects on p-face selectivity during hydride reduction and a systematic computational study demonstrates good predictability at the semi-empirical level.

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