✦ LIBER ✦

The biased reptation model of DNA gel electrophoresis: Mobility vs molecular size and gel concentration

✍ Scribed by Gary W. Slater; Jaan Noolandi

Publisher: Wiley (John Wiley & Sons)
Year: 1989
Tongue: English
Weight: 667 KB
Volume: 28
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360281011

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✦ Synopsis

The biased reptation model provides a good framework for interpreting the results of continuous field DNA electrophoresis experiments performed in agar-gels. Here we discuss the main features of the mobility-molecular size and mobility-gel concentration diagrams as obtained from new extensive computer simulations of the model. Our aim is to suggest a global and coherent picture of this widely used yet poorly understood experimental technique, and to point out the areas where a systematic experimental study is still needed.

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