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The bias and skewness of L1-estimates in regression

✍ Scribed by C.S. Withers

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 162 KB
Volume: 5
Category: Article
ISSN: 0167-9473
DOI: 10.1016/0167-9473(87)90053-3

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## Abstract This report presents the application of polynomial regression for estimating free energy differences using thermodynamic integration data, i.e., slope of free energy with respect to the switching variable λ. We employ linear regression to construct a polynomial that optimally fits the t