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The BH3 Domain of Bax is Sufficient for Interaction of Bax with itself and with other Family Members and it is Required for Induction of Apoptosis

✍ Scribed by Marjo Simonen; Hansjörg Keller; Jutta Heim


Book ID
115133760
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
765 KB
Volume
249
Category
Article
ISSN
1432-1327

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## Abstract Mutations in the __leucine‐rich repeat kinase 2__ (__LRRK2__) gene are the leading cause of genetically inherited Parkinson's disease (PD). Although this multidomain protein has been shown to have both GTPase and kinase activities through the Roc and MAPKKK domains, respectively, the pr