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The “best balance” allocation led to optimal balance in cluster-controlled trials

✍ Scribed by Esther de Hoop; Steven Teerenstra; Betsie G.I. van Gaal; Mirjam Moerbeek; George F. Borm


Book ID
116623972
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
105 KB
Volume
65
Category
Article
ISSN
0895-4356

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✍ Mikel Aickin 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 357 KB

Minimum likelihood allocation (MLA) is a new method for sequentially assigning subjects to treatment groups in a clinical trial. Its aim is to balance the trial, that is, to prevent various treatment groups from containing subjects who have much better or much worse prognoses than the average. The o