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The Bereitschaftspotential, l-DOPA and parkinson's disease

✍ Scribed by J.P.R Dick; R Cantello; O Buruma; M Gioux; R Benecke; B.L Day; J.C Rothwell; P.D Thompson; C.D Marsden


Book ID
115867197
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
899 KB
Volume
66
Category
Article
ISSN
0013-4694

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We compared the neuropsychological performance of patients with Parkinson's disease who were young at onset of the disease (mean age, 41.4 years) and had received prolonged L-dopa treatment (mean, 52.1 months) with nontreated patients of the same age. A similar comparison was made for patients who w

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## Abstract Previous fMRI motor studies in Parkinson's disease (PD) have suggested that L‐dopa may β€œnormalize” areas of hypo‐ and hyperactivity. However, results from these studies, which were largely based on analyzing BOLD signal amplitude, have been conflicting. Examining only amplitude changes