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The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats

✍ Scribed by Hilary J. Little; Stuart C. Taylor; David J. Nutt; Philip J. Cowen

Book ID
115879175
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
233 KB
Volume
107
Category
Article
ISSN
0014-2999

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Benzodiazepine antagonist RO 15-1788 par
Benzodiazepine antagonist RO 15-1788 partly reverses some anxiolytic effects of ethanol in the mouse
✍ Catherine Belzung; Elise Vogel; RenΓ© Misslin πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 379 KB

The effects of the benzodiazepine (BZD) receptor antagonist RO 15-1788 (3 mg/kg) on the anxiolytic properties of ethanol in mice confronted with a light/dark choice procedure and with the staircase test were investigated. RO 15-1788 reversed the effects of ethanol on some of the behavioural paramete