## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The benzilic ester rearrangement evidence for a set pathway in the benzilic ester and/or acid rearrangement
✍ Scribed by Constantinos G. Screttas; Maria Micha-Screttas; Constantine T. Cazianis
- Book ID
- 104221512
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 111 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract __tert__‐Butyl α,β‐dioxobutyrate (hydrate; **1d**) undergoes, at medium or high pH, the benzilic‐acid rearrangement with exclusive 1,2‐shift of the COO(__t__‐Bu) group; the same is true for the corresponding isopropyl ester **1c** and ethyl ester **1b** at high pH, whereas at lower pH,
## Abstract Aminocarbonyloxymethyl ester prodrugs are known to undergo rearrangement in aqueous solutions to form the corresponding __N__‐acylamine side product via an O → N intramolecular acyl transfer from the carbamate conjugate base. Novel aminocarbonyloxymethyl esters of diclofenac and flufena