✦ LIBER ✦

The Beckwith-Wiedemann syndrome phenotype and the risk of cancer

✍ Scribed by Schneid, H.; Vazquez, M.P.; Vacher, C.; Gourmelen, M.; Cabrol, S.; Le Bouc, Y.

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 112 KB
Volume: 28
Category: Article
ISSN: 0098-1532
DOI: 10.1002/(sici)1096-911x(199706)28:6<411::aid-mpo3>3.0.co;2-j

No coin nor oath required. For personal study only.

✦ Synopsis

Beckwith-Wiedemann syndrome (BWS) comprises of a number of childhood abnormalities, often associated with one or more tumors. Thirty-eight patients were investigated to determine clinical and/or biological signs associated with a tumor presence. Our patients exhibited a higher incidence of tumor development (21%) than that previously reported, underlying the care with which such patients should be followed, when particular clinical features are observed: visceromegaly affecting three organs (liver, kidney, spleen), and also family history with sign of BWS such as macroglossia, omphalocele, hemihypertrophy, embryonic tumor), high body weight at birth (> or = +2 standard deviations and diastasis recti.

📜 SIMILAR VOLUMES

Prenatal diagnosis of the Beckwith-Wiede

Prenatal diagnosis of the Beckwith-Wiedemann syndrome

✍ Winter, Susan C. ;Curry, Cynthia J. R. ;Smith, J. Charles ;Kassel, Stephen ;Mill 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB 👁 2 views

Familial occurrence of the Wiedemann-Bec

Familial occurrence of the Wiedemann-Beckwith syndrome and persistent fontanel

✍ Sommer, Annemarie ;Cutler, Edward A. ;Cohen, Benjamin L. ;Harper, Dwain ;Backes, 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB 👁 1 views

Wiedemann-Beckwith syndrome: Further pre

Wiedemann-Beckwith syndrome: Further prenatal characterization of the condition

✍ Reish, Orit ;Lerer, Israela ;Amiel, Aliza ;Heyman, Eli ;Herman, Arie ;Dolfin, Tz 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB 👁 2 views

Cloning of candidate genes involved in t

Cloning of candidate genes involved in the Beckwith-Wiedemann syndrome and childhood tumors

✍ Alders, M.; Bliek, J.; Redeker, B.; Ryan, A.; Feinberg, A.; Westerveld, A.; Litt 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 1 views

## INAUGURAL DR. ClULlO 1. D'ANGIO AWARD of adults who have been both cured of their tumor and In 1940, the diagnosis of Wilms' tumor was associated with the same poor prognosis as that of other forms of childhood cancer. The addition of radiation therapy, and then chemotherapy to the management

Giant omphalocele and “prune belly” sequ

Giant omphalocele and “prune belly” sequence as components of the Beckwith–Wiedemann syndrome

✍ Martine Sinico; Claudine Touboul; Bassam Haddad; Féréchté Encha-Razavi; Jean-Ber 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 1 views

Positional cloning of genes involved in

Positional cloning of genes involved in the Beckwith-Wiedemann syndrome, hemihypertrophy, and associated childhood tumors

✍ Mannens, Marcel; Alders, Marielle; Redeker, Bert; Bliek, Jet; Steenman, Marja; W 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 478 KB 👁 1 views

The Beckwith-Wiedemann syndrome (BWS) is an overgrowth malformation syndrome that occurs with an incidence of 1:13,700 births. There is a striking incidence of childhood tumors found in BWS patients. Various lines of investigation have localized "imprinted" genes involved in BWS and associated child