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The BCL-1, BCL-2, and BCL-3 oncogenes are involved in chronic lymphocytic leukemia: Detection by fluorescence in situ hybridization

✍ Scribed by Michael Lishner; Arie Lalkin; Ami Klein; Shay Yarkoni; Yosef Manor; Moshe Fejgin; Vallery Leytin; Mordchai Ravid; Aliza Amiel


Book ID
113253609
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
852 KB
Volume
85
Category
Article
ISSN
0165-4608

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✍ Yoshitaka Hosokawa; Ritsuro Suzuki; Tatsuroh Joh; Yumiko Maeda; Shigeo Nakamura; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 137 KB πŸ‘ 1 views

The cyclin D1/PRAD1 oncogene, a key regulator of the G 1 phase of the cell cycle, has been incriminated in the pathogenesis of human neoplasia. Cyclin D1 was also demonstrated to be identical to the long-sought bcl-1 oncogene in B-cell malignancies with the t(11;14)(q13;q32) translocation. We report