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The Bare Lymphocyte Syndrome: Molecular Clues to the Transcriptional Regulation of Major Histocompatibility Complex Class II Genes

โœ Scribed by Angela DeSandro; Uma M. Nagarajan; Jeremy M. Boss

Book ID
117852947
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
172 KB
Volume
65
Category
Article
ISSN
0002-9297

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The activation requirements for antigen-dependent proliferation of CD4+ T cells are well documented,while the events leading to the inactivation phase are poorly understood. Here, we tested the hypothesis that the lymphocyte-activation gene 3 (LAG-3), a second major histocompatibility complex (MHC)