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The balancing act of transcription factors C-1-1 and Runx2 in articular cartilage development

โœ Scribed by Masahiro Iwamoto; Eiki Koyama; Motomi Enomoto-Iwamoto; Maurizio Pacifici

Book ID
116289606
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
674 KB
Volume
328
Category
Article
ISSN
0006-291X

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## Abstract Identifying the genetic pathways that regulate skeletal development is necessary to correct a variety of cartilage and bone abnormalities. The Runx family of transcription factors play a fundamental role in organ development and cell differentiation. Initial studies have shown that both