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The B Cell in the Pathogenesis of Rheumatoid Arthritis

✍ Scribed by José Federico Díaz-González; Iván Ferraz Amaro


Book ID
118119771
Publisher
Elsevier Science
Year
2007
Tongue
Spanish
Weight
215 KB
Volume
3
Category
Article
ISSN
2173-5743

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✍ Mari A. Nowell; Peter J. Richards; Ceri A. Fielding; Simona Ognjanovic; Nick Top 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 542 KB

## Abstract ## Objective To determine whether interleukin‐6 (IL‐6) __trans__‐signaling directs the expression of pre–B cell colony‐enhancing factor (PBEF) in vitro and in vivo. ## Methods Complementary DNA from rheumatoid arthritis (RA) synovial fibroblasts treated with IL‐6 and soluble IL‐6 rec