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The aza-ene reaction of heterocyclic kentene aminals with enones: An unusual and efficient formation of imidazo[1,2-a] pyridine and imidazo[1,2,3-ij][1,8]naphthyridine derivatives

✍ Scribed by Jian-Heng Zhang; Mei-Xiang Wang; Zhi-Tang Huang

Book ID: 104260281
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 219 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)02132-7

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✦ Synopsis

Reaction of heterocyclic ketene animals with enones proceeds via an aza-ene addition followed by intramolecular cyclization to give imidazo[ I,t-alpyridine and imidazo[ I ,2,3-u] [I Jlnaphthyridine derivatives.

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