✦ LIBER ✦
The Australasian Gene Therapy Society : 4th Society Meeting, 27–29 April 2005, Rydges Hotel, Carlton, Melbourne, Victoria, Australia
- Book ID
- 102339542
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 356 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1099-498X
- DOI
- 10.1002/jgm.808
No coin nor oath required. For personal study only.
✦ Synopsis
The human engineered chromosome (HEC) technology represents a potentially exciting gene delivery system for the correction of human genetic disorders. However, for the full potential of HECs as chromosome-based gene delivery vectors to be realised, a number of key obstacles must be overcome. Five essential milestones must be satisfied before clinical studies can commence. These milestones are: to be able to clearly demonstrate (1) production of stable and fully characterisable HECs; (2) insertion and proper expression of desired genes on HECs; (3) purification of