We discovered that the hepatitis C virus (HCV) envelope glycoprotein E2 binds to human hepatoma cell lines independently of the previously proposed HCV receptor CD81. Comparative binding studies using recombinant E2 from the most prevalent 1a and 1b genotypes revealed that E2 recognition by hepatoma
The attachment receptor for hepatitis A virus
β Scribed by Stephen Locarnini
- Book ID
- 117680427
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 347 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0966-842X
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Hepatitis C virus (HCV) binds to different human cell lines in vitro. However, the efficiency of adsorption is very low due mainly to a relatively small fraction of the virus being able to bind to these cells. Free low density lipoprotein (LDL > 200 microg/ml) is able to block the attachment of HCV
In a previous study, we have identified endonexin I1 (E-11) on human liver plasma membranes as a specific, Ca2 + -dependent, small hepatitis B surface antigen (HBsAg)-binding protein. In this article, we describe the spontaneous development of anti-HBs antibodies in rabbits immunized with native or