The ATP switch model for ABC transporters
β Scribed by Higgins, Christopher F; Linton, Kenneth J
- Book ID
- 109966890
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 490 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1545-9993
- DOI
- 10.1038/nsmb836
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π SIMILAR VOLUMES
ABC transporters are a large superfamily of integral membrane proteins involved inATP-dependent transport across biological membranes. Members of this superfamily play roles in a number of phenomena of biomedical interest, including cystic fibrosis (CFTR) and multidrug resistance (P-glycoprotein, MR
## Abstract ABC transporters are a large and important family of membrane proteins involved in substrate transport across the membrane. The transported substrates are quite diverse, ranging from monatomic ions to large biomolecules. Consequently, some ABC transporters are involved in biomedically r