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The atomic force microscope: Can it be used to study biological molecules?

✍ Scribed by B.N.J. Persson

Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
252 KB
Volume
141
Category
Article
ISSN
0009-2614

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✦ Synopsis

The conditions necessary for studying biological molecules with the atomic force microscope are discussed. It is shown that in order to avoid large substrate deformations the microscope should be operated in its attractive mode where the van der Waals force between the tip and the substrate is z IO-" N and where the tip-substrate separation is of the order of 4-5 A.

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