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The ATM gene and the radiobiology of ataxia-telangiectasia

✍ Scribed by JORGENSEN, T. J.


Book ID
125438553
Publisher
Informa plc
Year
1996
Tongue
English
Weight
254 KB
Volume
69
Category
Article
ISSN
0955-3002

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The ataxia-telangiectasia mutated (ATM) gene, which is mutated in the autosomal recessive disorder ataxia-telangiectasia (AT), was isolated in 1995 by positional cloning. Although in vitro cell fusion studies had suggested that AT was genetically heterogeneous, all AT patients studied to date have b