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The asymmetric synthesis of allylglycine and other unnatural α-amino acids via zinc-mediated allylation of oximes in aqueous media

✍ Scribed by Stephen Hanessian; Rui-Yang Yang


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
206 KB
Volume
37
Category
Article
ISSN
0040-4039

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Zinc-mediated radical reaction of glyoxy
✍ Masafumi Ueda; Hideto Miyabe; Azusa Nishimura; Hisako Sugino; Takeaki Naito 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 130 KB

Alkyl radical addition to glyoxylic oxime ether and hydrazone in aqueous media was studied using zinc dust as a radical initiator. The zinc-mediated radical reaction of the hydrazone bearing a chiral camphorsultam provided the corresponding alkylated products with good diastereoselectivities, which