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The Astounding Chemistry of a 2-Amino-1,2-dihydroisoquinoline Derivative

✍ Scribed by Toni Durst; Jürgen A. Finke; Rolf Huisgen; Robert Temme


Publisher
John Wiley and Sons
Year
2000
Tongue
German
Weight
392 KB
Volume
83
Category
Article
ISSN
0018-019X

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A One-Pot Synthesis of 1,2-Dihydroisoqui
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## Abstract A four‐component reaction for the synthesis of 1,2‐dihydroisoquinoline derivatives is described. The __Huisgen__ 1,4‐dipolar intermediate, which is produced from isoquinoline and an electron‐deficient acetylene compound **1**, reacts with H~2~O in the presence of diketene to produce 1,2

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Spiro[pyrrole-3,2Ј-3(2H)-benzofuranones] 7 have been refluxing DMF, the spiro compounds yield tetrasubstituted pyrroles or compounds derived from chromenopyrroles. The synthesized by [4+2] cycloaddition of 2-arylidene-3(2H)benzofuranones with the 2-benzoyl-1,2-dihydroisoquinoline-regio-and stereoche