There is concern that hormone replacement therapy (HRT) increases the risk of breast cancer. We undertook a casecontrol study of this risk relationship within a cohort of 40-to 74-year-old women in Uppsala County, Sweden, who participated in mammography screening. Incident cases of breast cancer wer
The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
β Scribed by Eunjung Lee; Fredrick Schumacher; Juan Pablo Lewinger; Susan L Neuhausen; Hoda Anton-Culver; Pamela L Horn-Ross; Katherine D Henderson; Argyrios Ziogas; David Van Den Berg; Leslie Bernstein; Giske Ursin
- Book ID
- 118726746
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 309 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1465-5411
- DOI
- 10.1186/bcr2859
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## Abstract Epidemiological evidence suggests that intake of folate and other Bβvitamins and genetic variants in the oneβcarbon metabolism pathway could influence the risk of breast cancer. Previous studies have focused on 2 polymorphisms in the methylenetetrahydrofolate gene (__MTHFR__ A222V and E