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The Association of IL28B Polymorphism and Graft Survival in Patients with Hepatitis C Undergoing Liver Transplantation

✍ Scribed by Allam, Sridhar R.; Krüger, Bernd; Mehrotra, Anita; Schiano, Thomas; Schröppel, Bernd; Murphy, Barbara; Fung, James

Book ID: 120247679
Publisher: Public Library of Science
Year: 2013
Tongue: English
Weight: 398 KB
Volume: 8
Category: Article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0054854

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Polymorphism in the interleukin-28B (IL28B) gene region, encoding interferon (IFN)-k3, is strongly predictive of response to antiviral treatment in the nontransplant setting. We sought to determine the prevalence and impact on clinical outcomes of donor and recipient IL28B genotypes among liver tran