The association of exon 3 VNTR polymorphism of the dopamine receptor D4 (DRD4) gene with alcoholism in Mexican Americans
β Scribed by Yanlei Du; Min Yang; Hung-Wen Yeh; Yu-Jui Yvonne Wan
- Book ID
- 116850047
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 115 KB
- Volume
- 177
- Category
- Article
- ISSN
- 0165-1781
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The dopamine D4 receptor (DRD4) gene exhibits a large amount of expressed polymorphism in humans. To understand the evolutionary history of the first exon of DRD4which in humans contains a polymorphic 12bp tandem duplication, a polymorphic 13bp deletion, and other rare variants-we examined the homol
The dopamine D4 receptor (DRD4) is a member of the D2-like dopamine receptor family. Polymorphisms at the DRD4 gene have been examined for association with a wide range of neuropsychiatric disorders and normal behavioral variation. The DRD4 gene is unusual in its high amount of expressed polymorphis