## LETTERS trexate therapy for psoriasis carcinogenic? A modified retrospective-perspective-prospective analysis.
The association of amyloid deposits and osteoarthritis
โ Scribed by Michael S. Egan; Don L. Goldenberg; Alan S. Cohen; David Segal
- Book ID
- 102751282
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 554 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Ten of eighteen consecutive patients who underwent total knee or hip arthroplasty for osteoarthritis had amyloid present in the surgically removed articular tissues. It was found in 6 of 13 cartilage specimens, 4 of 18 articular capsules, and 2 of 16 synovial membranes. In 3 of the cartilage specimens, the amyloid was adjacent to focal deposits of calcium pyrophosphate dihydrate crystals. Therefore, deposits of amyloid are not uncommon in osteoarthritis and may be more than incidental findings.
๐ SIMILAR VOLUMES
## Abstract ## Objective The identified osteoarthritis (OA) susceptibility genes are mainly active in skeletal development and could thus affect joint geometry. Because nonoptimal joint geometry is a risk factor for the development of OA, we investigated if and how the path that leads from nonopti