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The Association Between Selected Risk Factors for Pancreatic Cancer and the Expression of p53 and K-ras Codon 12 Mutations

✍ Scribed by Fryzek, Jon P. ;Garabrant, David H. ;Schenk, Maryjean ;Kinnard, Margaret ;Greenson, Joel K. ;Sarkar, Fazlul H.


Book ID
113093448
Publisher
Springer
Year
2007
Tongue
English
Weight
109 KB
Category
Article
ISSN
1537-3649

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Mutations in codon I 2 of K-ras occur in a high proportion of pancreatic cancer cases. Although there is evidence that p53 mutations also occur in this tumor, few studies have been reported to date and no comparison has been made of K-ras and p53 mutations in the same tissues. Single-strand conforma