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The association between hyperuricemia and the Trp64Arg polymorphism of the beta-3 adrenergic receptor

✍ Scribed by Young Hee Rho; Seong Jae Choi; Young Ho Lee; Jong Dae Ji; Gwan Gyu Song

Publisher: Springer
Year: 2007
Tongue: English
Weight: 259 KB
Volume: 27
Category: Article
ISSN: 0172-8172
DOI: 10.1007/s00296-006-0300-7

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Background The beta-3-adrenergic receptor (b3AR) stimulates lipolysis and thermogenesis in adipocytes. The Trp64Arg b3AR variant is associated in some, but not all, studies with an earlier onset of Type 2 diabetes mellitus and features of the insulin resistance syndrome. Functional studies as to the