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The association between CHRN genetic variants and dizziness at first inhalation of cigarette smoke

✍ Scribed by Pedneault, Maxime; Labbe, Aurélie; Roy-Gagnon, Marie-Hélène; Low, Nancy C.; Dugas, Erika; Engert, James C.; O'Loughlin, Jennifer


Book ID
123433692
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
223 KB
Volume
39
Category
Article
ISSN
0306-4603

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## Abstract Cigarette smoke contains polycyclic hydrocarbons and arylamines that may both be activated by sulfotransferase, encoded by __SULT1A1__. A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association betwe