We describe a patient with relapsing polychondritis in whom aortic valve inflammation developed 3 years after diagnosis, when the polychondritis had been in apparent remission for an extended period of time. Infection and cardiac involvement can be significant complications of relapsing polychondrit
The arthropathy of relapsing polychondritis
โ Scribed by Michael O'Hanlan; Lawrence P. McAdam; Rodney Bluestone; Carl M. Pearson
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 377 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0004-3591
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Background. Relapsing polychondritis involving the upper airway is a rare cause of airflow obstruction and hoarseness. The diagnosis of relapsing polychondritis depends on clinical signs, characteristic findings on cartilage biopsy, and response to treatment. Delays in diagnosis and treatment can in
Objective. To characterize and clone T cells specific for type II collagen (CII) in a patient with relapsing polychondritis (RP) and to establish whether the immunodominant epitope of CII determined in HLA transgenic mice is used in the human autoimmune response to CII. Methods. T cell responses to