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The Arterial Pole of the Mouse Heart Forms from Fgf10-Expressing Cells in Pharyngeal Mesoderm

✍ Scribed by Robert G. Kelly; Nigel A. Brown; Margaret E. Buckingham

Book ID: 117795057
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 279 KB
Volume: 1
Category: Article
ISSN: 1534-5807
DOI: 10.1016/s1534-5807(01)00040-5

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Cover Picture: The cover image features a frozen section from an embryonic day 16 mouse spleen stained by immunofluorescence to demonstrate the presence and location of lymphoid tissue inducer (LTi) cells. Withers et al. (pp. 3240–3245) show that these cells form the focus of lymphocyte accumulation in the developing mouse spleen. Red staining for CD45 marks haemopoietic cells, green shows IL-7Rα expression, and CD4 expression is in blue. LTi cells that express all markers (in white) cluster around blood vessels in the embryonic spleen where signalling to stromal cells initiates lymphocyte recruitment. – Eur. J. Immunol. 11/2007

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