A LIKELIHOOD APPROACH TO META-ANALYSIS W
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REBECCA J. HARDY; SIMON G. THOMPSON
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Article
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1996
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John Wiley and Sons
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English
β 694 KB
In a meta-analysis of a set of clinical trials, a crucial but problematic component is providing an estimate and confidence interval for the overall treatment effect 8. Since in the presence of heterogeneity a fixed effect approach yields an artificially narrow confidence interval for 0, the random