The application of ultrasound to N-methylation of diazacoronands

✍ Scribed by Janusz Jurczak; Ryszard Ostaszewski

• Book ID: 104217934
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 131 KB
• Volume: 29
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)82493-4

✦ Synopsis

The application of ultrasound to N-methylation of variety of diazacoronands by methyl iodide under phase transfer conditions leads to N,N'-dimethyl diazacoronands in almost quantitative yields. N,N'-Diazacoronands of type 2 are used as macrocyclic subunits forming binding sites for ammonium groups in synthetic mole&lar receptors such as cryptands and cylindrical macrotricycles.'N,N'-Diazacoronands of this type serve also as key substrates in the high-pressure method of the synthesis of cryptands (Scheme l).' methylotion 40 2 de 21' 3