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The application of the genetic algorithm to the minimization of potential energy functions

✍ Scribed by Scott M. Le Grand; Kenneth M. Merz


Publisher
Springer US
Year
1993
Tongue
English
Weight
1013 KB
Volume
3
Category
Article
ISSN
0925-5001

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## Abstract We present a method that can reduce conformational energy calculations for an arbitrary peptide consisting of __n__ residues (__n__‐peptide) to the complexity of a computation for (Gly)~__n__~. This reduction, and the concomitant savings in computer time, is accomplished by replacing al