The application of pyrolysis methylation and esterification to the mass spectrometric sequencing of small peptides

✍ Scribed by G.M. Schier; J. Korth; B. Halpern

• Book ID: 104245462
• Publisher: Elsevier Science
• Year: 1972
• Tongue: French
• Weight: 171 KB
• Volume: 13
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)94381-3

✦ Synopsis

Established methods for the mass spectrometric sequence analysis of peptides require time-consuming chemical processing and manipulations to convert the peptides into suitable volatile derivatives 192 . We now describe a simple procedure for the amino acid sequencing of small peptides (2 -8 amino acid residues), which is based on the quantitative pyrolitic conversion of a peptide tri-