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The apparent positive cooperativity of in vivo [3H]PK-11195 binding in mouse fibrosarcoma

✍ Scribed by Sotaro Momosaki; Rie Hosoi; Nobuhiko Takai; Antony Gee; Osamu Inoue


Book ID
116799004
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
269 KB
Volume
33
Category
Article
ISSN
0969-8051

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## Abstract In mammalian CNS, the peripheral‐type benzodiazepine receptor (PTBR) is localized on the outer mitochondrial membrane within the astrocytes and microglia. The main function of PTBR is to transport cholesterol across the mitochondrial membrane to the site of neurosteroid biosynthesis. Th